Patent Ductus Arteriosus (PDA)
Overview
Patent ductus arteriosus (PDA) is a
heart defect found in the days or weeks after birth. The ductus arteriosus is a normal
blood vessel that's part of fetal blood circulation before a baby is born. It’s an
extra
blood vessel that connects two arteries: the pulmonary artery and the aorta. The
pulmonary artery carries blood from the heart to the lungs. The aorta carries blood
from
the heart to the body. Before birth, the ductus arteriosus lets blood go around (bypass)
the lungs. This is because the baby gets oxygen from the mother through the
placenta.
All babies are born with
this opening between the aorta and the pulmonary artery. But it often closes on its
own
shortly after birth, once the baby breathes on their own and inflates their lungs.
If it
stays open (patent), it's called patent ductus arteriosus. With PDA, extra blood flows
to the lungs. If the PDA is large, too much blood goes to the lungs. The blood vessels
and the lungs have to work much harder to handle the extra blood. This can lead to
fluid
buildup in the lungs. The baby can have a harder time breathing and feeding.
PDA occurs twice as often in girls
as in boys.
Causes
Experts don't know exactly why PDA occurs. It's more common in babies
born prematurely. PDA can also occur along with other heart defects.
Symptoms
The size of the opening between the
aorta and the pulmonary artery will affect symptoms. If your baby has a small opening,
they may not have symptoms. If your baby has a larger opening, they may have symptoms.
These are the most common symptoms of PDA:
-
Skin that turns a blue color from not getting enough oxygen (cyanosis)
-
Tiredness
-
Fast or hard breathing
-
Trouble feeding, tiredness while feeding, or sweating during feeding
-
Infections
-
Poor weight gain
-
Frequent respiratory infections
-
In older children, trouble doing activities
The symptoms of PDA can seem like
other health conditions. Have your child see their health care provider for a
diagnosis.
Diagnosis
The provider will ask about your
baby’s symptoms and health history. They will give your baby a physical exam. The
provider may find a heart murmur or other symptoms during an exam. The provider may
refer your baby to a pediatric cardiologist. This is a provider with special training
to
diagnose and treat heart problems in children.
The cardiologist will also check
your baby and listen to the heart and lungs. The details about the heart murmur will
help the provider make the diagnosis. Your baby may need tests, such as:
-
Echocardiogram (echo). An echo uses sound waves
to make a moving picture of the heart and heart valves. An echo shows the blood
flow pattern through the PDA. It also shows how large the opening is and how much
blood is passing through it. An echo is the most common way that a PDA is
diagnosed.
-
Chest X-ray. A chest X-ray may show an enlarged
heart and lung changes in a baby with PDA.
Treatment
Treatment will depend on your child’s symptoms, age, and general health. It will also
depend on how severe the condition is.
A small PDA will often close on its
own as your child grows. A PDA that causes symptoms will need to be treated with
medicine, cardiac catheterization, or surgery. The cardiologist will check from time
to
time to see if the PDA is closing on its own. If a PDA does not close, it will be
fixed
to prevent lung problems. Treatment may include the following.
Medicines
Your baby may need medicines to
help the heart work better.
-
In premature infants, the medicine indomethacin may help close the PDA. It's
given through an IV (intravenous) line. Indomethacin stimulates the muscles
inside the PDA to tighten. This closes the connection. Your
child's cardiologist can answer any questions you may have about this
treatment.
-
Some babies may need medicine to help the heart and lungs work better.
Sometimes a baby may need medicine such as diuretics (water pills). Diuretics
help the kidneys remove extra fluid from the body. This may be needed when the
heart is not working well. Or it may be needed if the blood vessels in the
lungs have to make room for more blood flow, as with a PDA.
Nutrition
Most infants with PDA eat and
grow normally. Some premature infants or those infants with large PDAs may get tired
when feeding. They may not be able to eat enough to gain weight. Nutrition choices
include:
-
High-calorie supplements. Special nutritional
supplements may be added to formula or pumped breastmilk to increase the number
of calories. Your baby can drink less and still have enough calories to grow
correctly.
-
Supplemental tube feedings. Supplemental
feedings are given through a small, flexible tube. The tube passes through the
nose or mouth, down the food pipe (esophagus), and into the stomach. The
feedings can either be added to or take the place of bottle-feedings. Infants
who can drink part of their bottles, but not all, may be fed the rest through
the feeding tube. Babies who are too tired to bottle-feed may get all their
formula or breastmilk through the feeding tube.
Cardiac catheterization (therapeutic cardiac cath)
For this test, your baby will be given medicine to relax
(sedation). The provider will put a thin, flexible tube (catheter) into a blood
vessel in the groin. They will guide the catheter through the large blood vessel in
the groin to the area of the PDA. The catheter will be placed in the PDA. Dye may
be
injected at this time to help the provider put the catheter in the right place. A
coil or closure device, which is attached to the catheter, will then be placed in
the
PDA. This will stop blood from flowing through the PDA. Once the coil or device is
in
the correct position, it will be released from the catheter. Then the catheter will
be removed.
Surgery
Surgery can close PDAs. Surgical
closure is often advised for babies younger than 6 months who have large defects and
symptoms, such as poor weight gain and fast breathing. For babies who don't have
symptoms, any surgery may be delayed until after age 6 to 12 months. Your child's
cardiologist will advise when the surgery should be done. It is done under general
anesthesia so your child will be asleep. Surgery closes the PDA with stitches or
clips. This stops the extra blood from getting into the lungs.
Complications
If not treated, PDA may lead to long-term lung damage. It can also
damage the blood vessels in the lungs. But this is not common because most children
will
have been treated for their PDA before the lungs and blood vessels get damaged.
Living with
-
If your child is discharged
home before having a repair procedure, you will be shown how to feed and give
medicine to your child. You will also be taught what symptoms to report to your
child's provider.
-
When your child is discharged
after the PDA repair, you may give them pain medicine such as acetaminophen or
ibuprofen to keep them comfortable. Your child's cardiac team will talk about pain
control before your child goes home.
-
Often infants who fed poorly
before surgery have more energy once they recover. They begin to eat better and
gain weight faster.
-
Within a few weeks after
surgery, older children are often fully recovered and able to do normal
activities.
-
You will get other
instructions from your child's cardiac team and the hospital staff.
-
In premature infants, the
outlook after PDA surgical repair depends on gestational age and overall
health.
-
In children born full-term,
early diagnosis and repair of PDA lets them live normal, healthy lives. Activity
levels, appetite, and growth should return to normal. Your child's cardiologist
may advise that your child take antibiotics to prevent infection in the heart
lining and valves (bacterial endocarditis).
-
In children with large PDAs
diagnosed very late or never repaired, the outlook is uncertain. They are at risk
for increased blood pressure in the blood vessels of the lungs (pulmonary
hypertension). These children should get follow-up at a care center that
specializes in congenital heart disease.
-
Talk with your
child's cardiologist about your child’s outlook.
When to Call a Healthcare Provider
Call your child's provider if your child's symptoms get worse or if
new symptoms develop, especially breathing or feeding problems.
Key Points
-
PDA is a heart defect found in the days or weeks after birth.
-
It occurs because a normal fetal connection between the aorta and the pulmonary
artery does not close as it should after birth.
-
PDA happens most often in premature infants. It often occurs with other congenital
heart defects.
-
A small PDA may close on its own as your child grows. If it is large or does not
close, your child will need a repair procedure.
-
An infant or child with PDA will be cared for by a pediatric cardiologist.
-
Most children with a fixed PDA will live normal, healthy lives.
Next Steps
Tips to help you get the most from
a visit to your child’s provider:
-
Know the reason for the visit and what you want to happen.
-
Before your visit, write down questions you want answered.
-
At the visit, write down the name of a new diagnosis and any new medicines,
treatments, or tests. Also write down any new instructions your provider gives you
for your child.
-
Know why a new medicine or treatment is prescribed and how it will help your
child. Also know what the side effects are and when they should be reported.
-
Ask if your child’s condition can be treated in other ways.
-
Know why a test or procedure is recommended and what the results could mean.
-
Know what to expect if your child does not take the medicine or have the test or
procedure.
-
If your child has a follow-up appointment, write down the date, time, and purpose
for that visit.
-
Know how you can contact your child’s provider after office hours. This is
important if your child becomes ill and you have questions or need advice.