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Pediatric Hematology Referral Guidelines


Specializing in the diagnosis and management of hematological disorders, the Hematology practice at Valley Children’s provides consultations 24 hours a day. We provide care for a large pediatric patient population with hemophilia and other bleeding disorders, hypercoagulabilities, thalassemia and other hemoglobinopathies, iron deficiencies, Fanconi anemia, Diamond-Blackfan anemia and other bone marrow failure syndromes.

Our team performs outpatient blood, platelet and immune-globulin transfusions for our pediatric patients who require these regimens. Our federally funded Hemophilia Treatment Center – the only one in Central California – participates in the Centers for Disease Control and Prevention’s ongoing surveillance studies related to bleeding and clotting disorders.

Valley Children’s hematology specialists also collaborate with other expert hematologists nationwide to offer the newest treatments for thalassemia, sickle cell disease and iron overload.

Our hematology specialists are always available for consultations and urgent patient appointments.

Refer to Hematology

Refer to Hematology online through CareLink or our referral portal, or refer via fax.

Refer a patient

Hematology Office Numbers

Contact Pediatric Hematology via phone (559-353-5460) or fax (559-353-5095).

Contact a Physician Liaison

Physicians can reach a physician liaison for help with referrals or other questions by calling 559-353-7229.

The following guidelines may not apply to many individual patient situations. Please contact us any time at the numbers provided to discuss your case further.

Group Condition Pre-Referral Work-up When to Refer
Anemias Iron deficiency

Other key history: diet, blood loss

Labs: CBC, retic, iron, TIBC, ferritin, lead

Symptomatic and/or non-responsive to oral iron therapy
Hereditary spherocytosis

Other key history: family history

Osmotic fragility test

Labs: CBC, retic, bilirubin

Confirmed or suspected diagnosis of hereditary spherocytosis
Sickle cell; Thalassemia Labs: CBC, retic, bili, hemoglobin electrophoresis Confirmed or suspected diagnosis of thalassemia and/or sickle cell anemia
Other cytopenias Thrombocytopenia Labs: CBC Platelet count below the normal range
Neutropenia Labs: CBC, retic, manual neutrophil count, if available Persistent ANC <1000 
Bleeding disorders Menorrhagia and / or Epistaxis and / or Easy Bruising Labs: CBC, PT, PTT, von Willebrand factor Ag and activity, factor VIII activity If labs abnormal, or bleeding / bruising
significant even if labs are normal / not done
von Willebrand disease  Labs: PTT, platelet function analysis, von Willebrand factor Ag and activity and multimer analysis, factor VIII activity Confirmed or suspected diagnosis of von Willebrand disease
Hemophilia Labs: PTT, factor VIII and / or IX activity   Confirmed or suspected diagnosis of hemophilia