Overview of Kidney Disorders in Children

Your child's body takes nutrients from food and converts them into energy. After your child's body has taken the nutrients it needs, waste products are left behind. They are left in the bowel and in the blood.

The kidneys and urinary system keep water and chemicals, such as potassium and sodium, in balance. They do this by removing a type of waste called urea from the blood. Urea is made when protein foods such as meat, poultry, and certain vegetables are broken down in the body. Urea is carried in the bloodstream to the kidneys.

The kidneys are a pair of purplish-brown organs. They are located below the ribs toward the middle of the back. They:

• Remove liquid waste from the blood in the form of urine

• Keep the correct balance of salts (electrolytes) and other substances in the blood

• Make erythropoietin, a hormone that helps red blood cells form

The kidneys remove urea from the blood through tiny filtering units called nephrons. Each kidney has about 1 million nephrons. They are in the medulla and the cortex. Each nephron is made up of a ball formed of small blood capillaries (a glomerulus) and a small tube called a renal tubule.

Urea, water, and other waste substances form into urine as it passes through the nephrons. They go down the renal tubules of the kidney. Urine then collects in the calyces and renal pelvis. It moves into the ureter. From the ureter, it flows down into the bladder.

The kidneys also do other important tasks:

• They make hormones that help keep blood pressure at a normal level and the heart working as it should.

• They change vitamin D into a form that can be used by the body’s tissues.

Nephrology is the branch of medicine that focuses on diagnosing and treating kidney problems. A nephrologist is a healthcare provider with special training in kidney problems. Other healthcare providers who treat kidney problems include primary care providers, pediatricians, and urologists.

Problems of the urinary system in children include different types of acute and chronic kidney failure. They also include urinary tract infections, blockages along the urinary tract, and problems present at birth.

Diseases of the kidneys often cause short-term or permanent changes to the small structures and vessels in the kidney. Frequent urinary tract infections can cause scarring in these structures. This can lead to kidney (renal) failure. Some diseases that cause kidney damage are:

• Glomerulonephritis

• Hemolytic uremic syndrome

• Polycystic kidney disease

• Hydronephrosis

• Urinary tract infections

Disorders of the genitourinary system in children are often found by fetal ultrasound before birth. Or they may be found in children who have a urinary tract infection. Your child's healthcare provider may order special tests. These tests may find an abnormality.

Some diseases of the kidney don't show up until later in life or after a child has a bacterial infection or an immune disorder.